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What health system strategies have low and middle income countries used to improve their maternal outcomes; A Rapid Response Brief
ACRES
2011
brief
Health Research

Background: Maternal morbidity and mortality worldwide is a major public health problem with unacceptable effects on families and nations. The maternal mortality ratio for sub-Saharan Africa is estimated at almost …

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What is involved in an efficient relationship between the Ministry of Health and teaching hospitals in order for both institutions to effectively meet their objectives; A Rapid Response Brief
ACRES
2011
brief
Health Research

Background: Teaching hospitals play a critical role in health care, medical education, and research. They are important to the Ministry of Health, which is responsible for providing quality healthcare to …

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What is the cost of diagnosing a new sputum smear positive TB case in children in low income settings; A Rapid Response Brief
ACRES
2011
brief
Health Research

Background: Diagnosing tuberculosis (TB) in children, particularly sputum smear-positive TB, presents challenges in low-income countries. The process involves a series of steps, including clinical examinations, tuberculin skin testing, and bacteriological …

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What is the effect of counseling in unwanted pregnancy; A Rapid Response Brief
ACRES
2011
brief
Health Research

Background: Unintended pregnancies affect a significant proportion of women worldwide, with a substantial number leading to induced abortions. In Uganda, a high prevalence of unintended pregnancies and a growing desire …

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What is the evidence for the effectiveness, safety and acceptability of âReady-To-Use Feedsâ; A Rapid Response Brief
ACRES
2011
brief
Health Research

Background: Malnutrition rates in Uganda are high, with a significant proportion of children under 5 suffering from chronic and acute malnutrition. Ready-to-Use Therapeutic Foods (RUTF), known as RUTAFA in Uganda, …

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What is the role of stem cell therapy in the management of noncommunicable diseases? How does it work and what are its implications on the health system; A Rapid Response Brief
ACRES
2011
brief
Health Research

Background: The World Health Organization (WHO) has reported a global shift from infectious to non-communicable diseases (NCDs), which are now the leading causes of death worldwide. Cell-based therapy, or regenerative …

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What role can the regional tier play in facilitating health services delivery; A Rapid Response Brief
ACRES
2011
brief
Health Research

Background: Many countries are adopting reforms such as decentralization to improve public systems and service delivery by transferring authority and resources closer to the end-users. The regional tier approach, involving …

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What would be the appropriate Health Financing Strategy for Uganda; A Rapid Response Brief
ACRES
2011
brief
Health Research

Background: In Uganda, nearly 5% of households face catastrophic health expenditures, and 2.3% are impoverished due to medical bills. This situation prompted the World Health Organization (WHO) to urge member …

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Management of (expensive) medical equipment; lessons from other countries; A Rapid Response Brief
ACRES
2012
brief
Health Research

Background: Effective health technology management (HTM) is essential for delivering safe, equitable, and quality health care. However, the rising costs of healthcare, driven in part by advancing medical technology, pose …

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What are the arrangement options for the accreditation of health service providers in low and middle-income countries (LMICs); A Rapid Response Brief
ACRES
2012
brief
Health Research

Background:National accreditation systems aim to provide accreditation services to healthcare facilities. Accreditation can be used at the national level for external assessment of health services and as a tool for …

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References (4020)

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Assessment of Clinical Outcomes Among Children and Adolescents Hospitalized With COVID-19 in 6 Sub-Saharan African Countries
Siedner MJ, Smith G, African Forum Res Educ Hlth AFREhl, Nachega JB, Sam-Agudu NA, Machekano RN, Rabie H, van der Zalm MM, Redfern A, Dramowski A and others...
2022
Journal, Article
Health Research

IMPORTANCE Little is known about COVID-19 outcomes among children and adolescents in sub-Saharan Africa, where preexisting comorbidities are prevalent.OBJECTIVE To assess the clinical outcomes and factors associated with outcomes among …

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Limitations of the International HIV Dementia Scale in the current era
Kiweewa F, Bahemana E, Langat R, Owuoth J, Adamu Y, AFRICOS Study Team, Milanini B, Paul R, Allen E, Polyak C and others...
2018
Journal, Article
Health Research

Objective: The International HIV Dementia Scale (IHDS) was developed as a tool to detect HIV-dementia in both industrialized and resource-limited settings. Studies employing the IHDS have produced mixed results, with …

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Decreasing time to antiretroviral therapy initiation after HIV diagnosis in a clinic-based observational cohort study in four African countries
Ake JA, Polyak CS, Crowell TA, Kiweewa F, Bahemana E, Maswai J, Owuoth J, Esber AL, Robb ML, Coakley P and others...
2020
Journal, Article
Health Research

Introduction World Health Organization (WHO) guidelines have shifted over time to recommend earlier initiation of antiretroviral therapy (ART) and now encourage ART initiation on the day of HIV diagnosis, if …

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Frequency and Predictors of HIV-Related Cognitive Impairment in East Africa: The Africa Cohort Study (AFRICOS)
Ake JA, Kiweewa F, Bahemana E, Maswai J, Langat R, Owuoth J, Nambuya A, AFRICOS Study Team, Milanini B, Paul R and others...
2020
Journal, Article
Health Research

Background: Medication adherence is a critical issue in achieving viral suppression targets, particularly in resource-limited countries. As HIV-related cognitive impairment (CI) impacts adherence, we examined frequency and predictors of CI …

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Impact of age on CD4 recovery and viral suppression over time among adults living with HIV who initiated antiretroviral therapy in the African Cohort Study
Ake JA, Polyak CS, Crowell TA, Kiweewa F, Maganga L, Bahemana E, Maswai J, Ganesan K, Valcour VG, Khamadi S and others...
2020
Journal, Article
Health Research

Introduction With increased use of antiretroviral therapy (ART), HIV mortality rates are declining and people living with HIV (PLWH) are surviving longer. We characterized CD4 recovery and viral suppression among …

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Factors associated with sexually transmitted infections among care-seeking adults in the African Cohort Study
Ake JA, Polyak CS, Crowell TA, Kiweewa F, Semwogerere M, Bahemana E, Maswai J, Owuoth J, Kibuuka H, Esber A and others...
2021
Journal, Article
Health Research

Objectives Sexually transmitted infections (STIs) are a major cause of morbidity. Understanding drivers of transmission can inform effective prevention programs. We describe STI prevalence and identify factors associated with STIs …

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Persons living with HIV in sero-discordant partnerships experience improved HIV care engagement compared with persons living with HIV in sero-concordant partnerships: a cross-sectional analysis of four African countries
Ake JA, Polyak CS, Crowell TA, Bahemana E, Maswai J, Owuoth J, Esber AL, Ganesan K, Kibuuka H, AFRICOS Study Team and others...
2021
Journal, Article
Health Research

Background Persons living with HIV (PLWH) who are members of sero-discordant and sero-concordant relationships may experience psychological stressors or motivators that affect HIV care. We assessed the association between sero-discordance …

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Pretreatment and Acquired Antiretroviral Drug Resistance Among Persons Living With HIV in Four African Countries
Ake JA, Polyak CS, Crowell TA, Kiweewa F, Bahemana E, Maswai J, Owuoth J, Eller LA, Coakley P, Kasembeli A and others...
2021
Journal, Article
Health Research

Background. Emerging HIV drug resistance (HIVDR) could jeopardize the success of standardized HIV management protocols in resource-limited settings. We characterized HIVDR among antiretroviral therapy (ART)-naive and experienced participants in the …

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Prevalence and predictors of food insecurity among people living with and without HIV in the African Cohort Study
Ake JA, Polyak CS, Crowell TA, Bahemana E, Maswai J, Owuoth J, Kibuuka H, Esber A, AFRICOS Study Grp, Dear N and others...
2022
Journal, Article
Health Research

Objective: We determined the prevalence and identified predictors of food insecurity in four African countries. Design: Cross-sectional analyses at study enrolment. Setting: From January 2013 to March 2020, people living …

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Weight gain during the dolutegravir transition in the African Cohort Study
Ake JA, Polyak CS, Crowell TA, Bahemana E, Maswai J, Owuoth J, Esber AL, Kibuuka H, AFRICOS Study Grp, Iroezindu M and others...
2022
Journal, Article
Health Research

Introduction Dolutegravir (DTG) has become a preferred component of first-line antiretroviral therapy (ART) in many settings but may be associated with excess weight gain. We evaluated changes in weight and …

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