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What health system strategies have low and middle income countries used to improve their maternal outcomes; A Rapid Response Brief
ACRES
2011
brief
Health Research

Background: Maternal morbidity and mortality worldwide is a major public health problem with unacceptable effects on families and nations. The maternal mortality ratio for sub-Saharan Africa is estimated at almost …

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What is involved in an efficient relationship between the Ministry of Health and teaching hospitals in order for both institutions to effectively meet their objectives; A Rapid Response Brief
ACRES
2011
brief
Health Research

Background: Teaching hospitals play a critical role in health care, medical education, and research. They are important to the Ministry of Health, which is responsible for providing quality healthcare to …

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What is the cost of diagnosing a new sputum smear positive TB case in children in low income settings; A Rapid Response Brief
ACRES
2011
brief
Health Research

Background: Diagnosing tuberculosis (TB) in children, particularly sputum smear-positive TB, presents challenges in low-income countries. The process involves a series of steps, including clinical examinations, tuberculin skin testing, and bacteriological …

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What is the effect of counseling in unwanted pregnancy; A Rapid Response Brief
ACRES
2011
brief
Health Research

Background: Unintended pregnancies affect a significant proportion of women worldwide, with a substantial number leading to induced abortions. In Uganda, a high prevalence of unintended pregnancies and a growing desire …

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What is the evidence for the effectiveness, safety and acceptability of âReady-To-Use Feedsâ; A Rapid Response Brief
ACRES
2011
brief
Health Research

Background: Malnutrition rates in Uganda are high, with a significant proportion of children under 5 suffering from chronic and acute malnutrition. Ready-to-Use Therapeutic Foods (RUTF), known as RUTAFA in Uganda, …

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What is the role of stem cell therapy in the management of noncommunicable diseases? How does it work and what are its implications on the health system; A Rapid Response Brief
ACRES
2011
brief
Health Research

Background: The World Health Organization (WHO) has reported a global shift from infectious to non-communicable diseases (NCDs), which are now the leading causes of death worldwide. Cell-based therapy, or regenerative …

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What role can the regional tier play in facilitating health services delivery; A Rapid Response Brief
ACRES
2011
brief
Health Research

Background: Many countries are adopting reforms such as decentralization to improve public systems and service delivery by transferring authority and resources closer to the end-users. The regional tier approach, involving …

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What would be the appropriate Health Financing Strategy for Uganda; A Rapid Response Brief
ACRES
2011
brief
Health Research

Background: In Uganda, nearly 5% of households face catastrophic health expenditures, and 2.3% are impoverished due to medical bills. This situation prompted the World Health Organization (WHO) to urge member …

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Management of (expensive) medical equipment; lessons from other countries; A Rapid Response Brief
ACRES
2012
brief
Health Research

Background: Effective health technology management (HTM) is essential for delivering safe, equitable, and quality health care. However, the rising costs of healthcare, driven in part by advancing medical technology, pose …

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What are the arrangement options for the accreditation of health service providers in low and middle-income countries (LMICs); A Rapid Response Brief
ACRES
2012
brief
Health Research

Background:National accreditation systems aim to provide accreditation services to healthcare facilities. Accreditation can be used at the national level for external assessment of health services and as a tool for …

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References (4020)

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Prevalence and risk factors for neural axis anomalies in idiopathic scoliosis: a systematic review
Heemskerk Johan L., Kruyt Moyo C., Colo Dino, Castelein René M., Kempen Diederik H. R.
2018
Journal, Article
Health Research

Background: There is ongoing controversy about the routine use of magnetic resonance imaging (MRI) preoperatively in patients with presumed idiopathic scoliosis (IS). Routine MRI can help identify possible causes for …

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Spinal Growth in Patients with Juvenile Idiopathic Scoliosis Treated with Boston Brace: A Retrospective Study
Heemskerk J.L., Wijdicks S.P.J., Altena M.C., Castelein R.M., Kruyt M.C., Kempen D.H.R.
2020
Journal, Article
Health Research

Study Design.Retrospective comparative cohort.Objective.The aim of this study was to determine whether spinal growth is restricted by brace treatment in patients with juvenile idiopathic scoliosis (JIS).Summary of Background Data.Spinal fusion …

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Ticagrelor versus placebo for the reduction of vaso-occlusive crises in pediatric sickle cell disease: the HESTIA3 study
Heeney M.M., Abboud M.R., Githanga J., Inusa B.P., Kanter J., Michelson A.D., Nduba V., Musiime V., Apte M., Inati A. and others...
2022
Journal, Article
Health Research

The phase 3 HESTIA3 study assessed the efficacy and safety of the reversible P2Y12 inhibitor ticagrelor versus placebo in preventing vaso-occlusive crises in pediatric patients with sickle cell disease (SCD). …

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Contraception, fertility planning and HIV-1 risk among African HIV-1 serodiscordant couples
Heffron Renee
2012
Dissertation
Health Research

The studies within this dissertation describe contraception and fertility planning and their relationship to HIV-1 risk among African HIV-1 serodiscordant couples. Specifically, this work 1) describes correlates of contraceptive use, …

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Preexposure prophylaxis is efficacious for HIV-1 prevention among women using depot medroxyprogesterone acetate for contraception
Celum C, Heffron R, Katabira E, Mugo N, Baeten J M, Were E, Kiarie J, Bukusi E A, Mujugira A, Frenkel L M and others...
2014
Journal, Article
Health Research

ObjectiveâTo evaluate pre-exposure prophylaxis (PrEP) efficacy for HIV-1 prevention amongwomen using depot medroxyprogesterone acetate (DMPA) for contraception and men whoseHIV-1 infected partners use DMPA.DesignâSecondary analysis of data from a randomized …

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PrEP as Peri-conception HIV Prevention for Women and Men
Heffron R, Mugo N, Pintye J, Matthews L T, Weber S
2016
Journal, Article
Health Research

Daily oral tenofovir (TDF)-based pre-exposure prophylaxis (PrEP) is an effective HIV prevention strategy and recommended for men and women with substantial risk of HIV acquisition. The peri-conception period, the stage …

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HIGH PrEP UPTAKE and LOW HIV VIREMIA WHEN PrEP IS INTEGRATED into UGANDAN ART CLINICS
Mujugira A., Heffron R., Muwonge T., Thomas D., Nambi F., Nakabugo L., Kibuuka J., Feutz E.L., Meisner A.A., Thomas K.K. and others...
2022
Journal, Article
Health Research

Background: Global scale-up of HIV (pre-exposure prophylaxis) PrEP includes targeting HIV-negative people in serodifferent partnerships with people living with HIV. There are few data to describe whether there is any …

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Cytomegalovirus infections in infants in Uganda: Newborn-mother pairs, neonates with sepsis, and infants with hydrocephalus
Bazira J, Smith J, Kiwanuka J, Mugamba J, Hehnly C, Ssentongo P, Bebell LM, Burgoine K, Fronterre C, Kumbakumba E and others...
2022
Journal, Article
Health Research

Objectives: To estimate the prevalence of cytomegalovirus (CMV) infections among newborn-mother pairs, neonates with sepsis, and infants with hydrocephalus in Uganda.Design and Methods: Three populations-newborn-mother pairs, neonates with sepsis, and …

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Type IV pili is a critical virulence factor in clinical isolates of Paenibacillus thiaminolyticus
Schiff S.J., Hehnly C., Shi A., Ssentongo P., Zhang L., Isaacs A., Morton S.U., Streck N., Erdmann-Gilmore P., Tolstoy I. and others...
2022
Journal, Article
Health Research

Hydrocephalus, the leading indication for childhood neurosurgery worldwide, is particularly prevalent in low-and-middle-income countries (LMICs). Hydrocephalus preceded by an infection, or postinfectious hydrocephalus (PIH), accounts for up to 60% of …

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Antiretroviral drugs for preventing mother-to-child transmission of HIV: A review of potential effects on HIV-exposed but uninfected children
Katabira Elly, Cahn Pedro, Heidari Shirin, Mofenson Lynne, Cotton Mark F., Marlink Richard
2011
Journal, Article
Health Research

The provision of antiretroviral drugs for the prevention of mother-to-child HIV transmission has been rising sharply in low- and middle-income countries. Changes to the World Health Organization guidelines support further …

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