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Does introducing deliveries at Health Center II improve maternal outcomes; A Rapid Response Brief
ACRES
2011
brief
Health Research

Background: In low and middle-income countries, a significant proportion of maternal deaths are due to preventable obstetric complications. Physical access to healthcare remains a substantial barrier in many regions, including …

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Dual employment of health workers: what is it and its impact, why is it present, and what steps the government can take; A Rapid Response Brief
ACRES
2011
brief
Health Research

Background: The government of Uganda, like many others worldwide, is concerned about dual employment (moonlighting) of health workers. Dual practice is common across countries, even those with strong regulations, and …

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How applicable are the 2010 WHO guidelines for infant feeding in the context of HIV in low-income countries like Uganda; A Rapid Response Brief
ACRES
2011
brief
Health Research

Background: Mother-to-child transmission (MTCT) is the primary way children contract HIV, and this can occur during pregnancy, childbirth, or breastfeeding. In resource-rich settings, mothers with HIV infection are counseled against …

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How can the sustainability of a public health (food fortification) program be ensured; A Rapid Response Brief
ACRES
2011
brief
Health Research

Background: Knowledge about health program planning, implementation, and evaluation is abundant, but information on health promotion program sustainability is less available and often fragmented. Sustainability is important to public health …

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Is there an application of Herbal Medicines (esp. D. Erecta) in the management of HIV/AIDS and Cancer; A Rapid Response Brief
ACRES
2011
brief
Health Research

Background: The use of herbal medicines among people with chronic illnesses, such as HIV/AIDS and cancer, is common, often due to perceived ineffectiveness of conventional medicine.Rapid Response Question: Is there …

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Knowledge Management: How can policy makers improve the use of data in policy discussions and development; A Rapid Response Brief
ACRES
2011
brief
Health Research

Background: A number of low- and middle-income countries are following the lead of high-income countries like Australia, UK, and Canada, and are increasingly using research evidence in policymaking and practice. …

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What are the different strategies to implement a bilateral government agreement on recruiting professional health workers from Uganda; A Rapid Response Brief
ACRES
2011
brief
Health Research

Background: Although only attracting growing attention in recent years, health-worker migration has raised concerns for several decades now. Earlier migration was voluntary and generally an individual initiation; in recent years …

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What are the policy options for re-centralization of the health sector in Uganda; A Rapid Response Brief
ACRES
2011
brief
Health Research

Background: Following World Bank and IMF-backed reforms in the 1990s, many low and middle-income countries decentralized their social sectors, including health. Despite some gains, a decline in services, especially for …

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What are the stem cell policies and regulations globally; A Rapid Response Brief
ACRES
2011
brief
Health Research

Background: This paper gives a general overview of the policies of countries in given regions and identifies a few countries for which the content will be analyzed and related to …

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What guidelines are present to facilitate the evaluation of a natural material extract as a larvicide; A Rapid Response Brief
ACRES
2011
brief
Health Research

Background: The World Health Organization (WHO) provides guidelines for evaluating mosquito larvicides, detailed in their "Guidelines for Laboratory and Field testing of Mosquito larvicides."Rapid Response Question: What guidelines are present …

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References (4020)

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A livelihood intervention to improve economic and psychosocial well-being in rural Uganda: Longitudinal pilot study
Tsai A.C., Bangsberg D.R., Atuhumuza E., Kakuhikire B., Suquillo D., Mushavi R., Perkins J.M., Venkataramani A.S., Weiser S.D.
2016
Journal, Article
Health Research
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The Effects of ACT Treatment and TS Prophylaxis on Plasmodium falciparum Gametocytemia in a Cohort of Young Ugandan Children
Kakuru A, Wanzira H, Kamya MR, Tappero JW, Arinaitwe E, Dorsey G, Homsy J, Bigira V, Muhindo M, Jagannathan P and others...
2013
Journal, Article
Health Research

Artemisinin-based combination therapies (ACTs) and trimethoprim-sulfamethoxazole (TS) prophylaxis are important tools for malaria control, but there are concerns about their effect on gametocytes, the stage of the parasite responsible for …

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Artemisinin-based combination therapies are efficacious and safe for treatment of uncomplicated malaria in HIV-infected ugandan children
Achan J, Kakuru A, Ikilezi G, Mwangwa F, Charlebois E, Havlir D, Ruel T, Arinaitwe E, Dorsey G, Kamya M R and others...
2014
Journal, Article
Health Research

Background.âArtemisinin-based combination therapies (ACTs) are highly efficacious and safe, but data from human immunodeficiency virus (HIV)âinfected children concurrently receiving antiretroviral therapy (ART) and ACTs are limited.Methods.âWe evaluated 28-day outcomes following …

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Dihydroartemisinin-Piperaquine for the Prevention of Malaria in Pregnancy
Kakuru A, Natureeba P, Clark TD, Kamya MR, Havlir DV, Dorsey G, Olwoch P, Charlebois ED, Ategeka J, Jagannathan P and others...
2016
Journal, Article
Health Research

BACKGROUNDIntermittent treatment with sulfadoxine-pyrimethamine is widely recommended for the prevention of malaria in pregnant women in Africa. However, with the spread of resistance to sulfadoxine-pyrimethamine, new interventions are needed.METHODSWe conducted …

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Malaria burden in a birth cohort of HIV-exposed uninfected Ugandan infants living in a high malaria transmission setting
Kakuru A, Ruel T, Natureeba P, Cohan D, Dorsey G, Kamya M R, Clark T D, Muhindo M K, Havlir D V
2016
Journal, Article
Health Research

AbstractBackground: HIV-exposed, uninfected (HEU) infants suffer high morbidity and mortality in the first year of life compared to HIV-unexposed, uninfected (HUU) infants, but accurate data on the contribution of malaria …

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ASSOCIATION BETWEEN INDOOR RESIDUAL SPRAYING OF INSECTICIDE AND IMPROVED BIRTH OUTCOMES AMONG HIV-INFECTED PREGNANT WOMEN IN UGANDA
et al, Kakuru A., Koss C., Natureeba P., Roh M., Shiboski S., Global Health Group Malaria Elimination Initiative U. S. A.
2017
Journal, Article
Health Research

WATERLIT Abstract: Despite effective interventions to prevent malaria during pregnancy, the risk of adverse birth outcomes among HIV-infected pregnant women living in sub-Saharan Africa remains high. A recent study demonstrated …

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Impact of Plasmodium falciparum malaria and intermittent preventive treatment of malaria in pregnancy on the risk of malaria in infants: a systematic review
Dorsey G., Kakuru A., Staedke S. G., Rogerson S., Chandramohan D.
2019
Journal, Article
Health Research

BACKGROUND: Studies of the association between malaria in pregnancy (MiP) and malaria during infancy have provided mixed results. A systematic review was conducted to evaluate available evidence on the impact …

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Impact of intermittent preventive treatment of malaria in pregnancy with dihydroartemisinin-piperaquine versus sulfadoxine-pyrimethamine on the incidence of malaria in infancy: A randomized controlled trial
Dorsey G., Kajubi R., Jagannathan P., Ochieng T., Kakuru A., Kamya M.R., Clark T.D., Havlir D.V., Chandramohan D., Ochokoru H. and others...
2020
Journal, Article
Health Research

Background: Intermittent preventive treatment of malaria during pregnancy (IPTp) with dihydroartemisinin-piperaquine (DP) significantly reduces the burden of malaria during pregnancy compared to sulfadoxine-pyrimethamine (SP), the current standard of care, but …

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Infant sex modifies associations between placental malaria and risk of malaria in infancy
Dorsey G., Kajubi R., Jagannathan P., Ochieng T., Kakuru A., Kamya M.R., Clark T.D., Havlir D.V., Chandramohan D., Ochokoru H. and others...
2020
Journal, Article
Health Research

Background: Placental malaria (PM) has been associated with a higher risk of malaria during infancy. However, it is unclear whether this association is causal, and is modified by infant sex, …

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Central Nervous System Tumors in Uganda: Outcomes of Surgical Treatment and Complications Assessed Through Telephone Survey
Haglund MM, Kiryabwire J, Muhumuza M, Ssenyonjo H, Mukasa J, Vaca SD, Nalwanga J, Grant GA, Kakusa BW, Xu LW
2019
Journal, Article
Health Research

BACKGROUND: Uganda has one of the largest unmet neurosurgical needs in the world, but has seen major improvements in neurosurgery-largely centered at Mulago National Referral Hospital (MNRH). This study implements …

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